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Gene Expression Data
Assay Details
Assay
Reference: J:146765 Golonzhka O, et al., Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7433208
Gene symbol: Enam
Gene name: enamelin
Antibody: anti-enamelin
Results
Specimen 3M: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present Regionally restricted 3M Ameloblasts developed only on the labial side, while epithelial cells populated the lingual aspect.

Specimen 3N: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Weak 3N Severely reduced expression compared with the wild-type. Ameloblasts were reduced in size.

Specimen 3O: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present Regionally restricted 3O Ameloblasts developed only on the labial side, while epithelial cells populated the lingual aspect.

Specimen 3P: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present 3P A secondary ameloblast-like layer was present on the lingual side in the mutant.

Specimen 3Q: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Present 3Q
TS26: stratum intermedium Present 3Q

Specimen 3R: embryonic day 18.5; Bcl11btm1.2Leid/Bcl11btm1.2Leid (more )
Structure Cell Type Level Pattern Image Note
TS26: inner enamel epithelium ameloblast Weak 3R Ameloblasts were with deformed or absent adhesion points on the labial side.
TS26: stratum intermedium Present 3R


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory