Gene Expression Data
Assay Details
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Assay
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Reference:
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J:75868
Lu QR, et al., Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7432579
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Gene symbol:
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Sox10
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Gene name:
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SRY (sex determining region Y)-box 10
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Results
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Specimen
2A +/+ E12.5:
embryonic day 12.5
(more  )
Specimen
2A +/+ E12.5:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: spinal cord ventricular layer |
spinal cord oligodendrocyte |
Present |
Regionally restricted |
2A Sox10 E12.5 +/+
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Expressed in early oligodendrocytes in the ventral ventricular zone of the neural tube at the forelimb level.
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Specimen
2A -/- E12.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
2A +/+ E14.5:
embryonic day 14.5
(more )
Specimen
2A +/+ E14.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: spinal cord |
spinal cord oligodendrocyte |
Present |
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2A Sox10 E14.5 +/+
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Specimen
2A -/- E14.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
2A +/+ E18.5:
embryonic day 18.5
(more )
Specimen
2A +/+ E18.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord |
spinal cord oligodendrocyte |
Present |
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2A Sox10 E18.5 +/+
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Specimen
2A -/- E18.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
2C Olig1+/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig1tm1(cre)Rth/Olig1+
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
2C Olig1-/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig1tm1(cre)Rth/Olig1tm1(cre)Rth
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
3A dorsal +/+:
embryonic day 18.5
(more )
Specimen
3A dorsal +/+:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: forebrain |
oligodendrocyte precursor cell |
Present |
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3A-5
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Specimen
3A dorsal -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: forebrain |
oligodendrocyte precursor cell |
Present |
Regionally restricted |
3A-6
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There was no expression in the dorsal region. Only a small collection of positive cells in the ventral region.
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Specimen
3A ventral +/+:
embryonic day 18.5
(more )
Specimen
3A ventral +/+:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: forebrain |
oligodendrocyte precursor cell |
Present |
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3A-7
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Specimen
3A ventral -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: forebrain |
oligodendrocyte precursor cell |
Present |
Regionally restricted |
3A-8
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Only a small collection of positive cells in the ventral region.
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Specimen
3B +/+:
embryonic day 18.5
(more )
Specimen
3B +/+:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: hindbrain |
oligodendrocyte precursor cell |
Present |
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3B-7
,
3B-5
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Specimen
3B -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS26: hindbrain |
oligodendrocyte precursor cell |
Present |
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3B-8
,
3B-6
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Nearly normal numbers of positive cells compared with the wild-type.
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Specimen
7A:
embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor +, Olig1tm1(cre)Rth/Olig1 +
(more )
Note: Conditional mutant. Double labeled: purple - Sox10; blue - Cre reporter.
Specimen
7A:
(close )
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Genetic Background:
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involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J
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Mutant Allele(s):
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Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Olig1tm1(cre)Rth/Olig1+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant. Double labeled: purple - Sox10; blue - Cre reporter.
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: spinal cord lateral wall |
spinal cord oligodendrocyte |
Present |
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7A 12.5 LacZ/Sox10
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Expressed in early oligodendrocytes. Colocalization with Olig1-Cre linage expression was seen.
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Analysis Tools