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Gene Expression Data
Assay Details
Assay
Reference: J:198469 Yang Y, et al., Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation. Dev Biol. 2013 Jun 15;378(2):94-106
Assay type: RNA in situ
MGI Accession ID: MGI:7432366
Gene symbol: Mbp
Gene name: myelin basic protein
Probe: MBP probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Horseradish peroxidase
Results
Specimen 2B: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2B
TS28: corpus callosum Present 2B
Specimen 2C: postnatal day 7; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2C Reduced expression compared with the wild-type.
TS28: corpus callosum Present 2C Reduced expression compared with the wild-type.
Specimen 2F: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2F
TS28: corpus callosum Present 2F
Specimen 2G: postnatal day 14; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 2G More severely reduced expression compared with the wild-type.
TS28: corpus callosum Present 2G More severely reduced expression compared with the wild-type.
Specimen 3A: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present 3A
Specimen 3B: postnatal day 14; Cdk5tm1Bibb/Cdk5tm1Bibb, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: spinal cord Present 3B Relatively uniform reduced expression compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory