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Gene Expression Data
Assay Details
Assay
Reference: J:161290 Chizhikov VV, et al., Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10725-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431476
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: Anti-Tbr2
Results
Specimen 3G: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: rhombic lip Present 3G
Specimen 3H: embryonic day 18.0; Lmx1adr/Lmx1adr (more )
Structure Level Pattern Image Note
TS26: metencephalon Present Regionally restricted 3H Virtually no rhombic lip was detected in these embryos. A few immunopositive cells were occasionally found in the area corresponding to the mutant rhombic lip.
Specimen S1I: postnatal day 3 (more )
Note: Double labeled: green - Eomes; red - Lmx1a (assay MGI:7431456).
Structure Cell Type Level Pattern Image Note
TS27: cerebellum internal granule cell layer unipolar brush cell Present S1I Eomes is a unipolar brush cell marker. Co-expression was detected with Lmx1a.
Specimen S4D: postnatal day 3; Gdf7tm3(cre)Tmj/Gdf7+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Eomes; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: cerebellum vermis unipolar brush cell Present Regionally restricted S4D Expression was detected in unipolar brush cells in the most posterior lobe.
Specimen S4E: postnatal day 3; Gdf7tm3(cre)Tmj/Gdf7+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Lmx1adr/Lmx1adr (more )
Note: Conditional mutant. Double labeled: red - Eomes; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: cerebellum vermis unipolar brush cell Present Regionally restricted S4E Some beta-gal+ cells in the dreher cerebellum co-expressed with Eomes indicating they adopted the fate of unipolar brush cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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