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Gene Expression Data
Assay Details
Assay
Reference: J:332497 Tang X, et al., EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427875
Gene symbol: Emc4
Gene name: ER membrane protein complex subunit 4
Antibody: anti-EMC4 (ab184544)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Anti-EMC4 (ab236141) MGI:7427871 may have been used in this assay.
Results
Specimen 1G control: embryonic day 16.5; Emc3tm1c(EUCOMM)Wtsi/Emc3tm1c(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS24: lung epithelium Present 1G control
TS24: lung mesenchyme Present 1G control
Specimen 1G Emc3 cKO: embryonic day 16.5; Emc3tm1c(EUCOMM)Wtsi/Emc3tm1c(EUCOMM)Wtsi, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: lung epithelium Present 1G Emc3 cKO Expression persisted in respiratory epithelial cells.
TS24: lung mesenchyme Weak 1G Emc3 cKO Expression decreased in mesenchyme compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory