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Gene Expression Data
Assay Details
Assay
Reference: J:199435 Barraud P, et al., Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427757
Gene symbol: Gnrh1
Gene name: gonadotropin releasing hormone 1
Antibody: anti-GnRH1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen E14.5 +/+: embryonic day 14.5 (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS22: brain gonadotropin-releasing hormone neuron Present Single cells
Specimen E14.5 +/-: embryonic day 14.5; Sox10tm1Weg/Sox10+ (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS22: brain gonadotropin-releasing hormone neuron Present Single cells The percentage of GnRH-positive neurons that have entered the brain is significantly reduced in the heterozygotes.
Specimen E14.5 -/-: embryonic day 14.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS22: brain gonadotropin-releasing hormone neuron Present Single cells The percentage of GnRH-positive neurons that have entered the brain is significantly reduced in the homozygotes.
Specimen E16.5 +/+: embryonic day 16.5 (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS24: brain gonadotropin-releasing hormone neuron Present Single cells
Specimen E16.5 +/-: embryonic day 16.5; Sox10tm1Weg/Sox10+ (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS24: brain gonadotropin-releasing hormone neuron Present Single cells The percentage of GnRH-positive neurons that have entered the brain is no longer significantly reduced in the heterozygotes.
Specimen E16.5 -/-: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: These data are quantified in Fig. 5D.
Structure Cell Type Level Pattern Image Note
TS24: brain gonadotropin-releasing hormone neuron Present Single cells The percentage of GnRH-positive neurons that have entered the brain is reduced four-fold in the homozygotes.
Specimen 5E: embryonic day 16.5 (more )
Note: Coronal section. Double labeled: white - Gnrh1; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS24: hypothalamus gonadotropin-releasing hormone neuron Present 5E1
Specimen 5F: embryonic day 16.5; Sox10tm1Weg/Sox10tm1Weg (more )
Note: Coronal section. Double labeled: magenta - Gnrh1; green - Tubb3 (assay MGI:7427814).
Structure Cell Type Level Pattern Image Note
TS24: nasal cavity mucosa gonadotropin-releasing hormone neuron Present 5F , 5F1 Expressing cells are seen in the olfactory mucosa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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