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Gene Expression Data
Assay Details
Assay
Reference: J:320419 Li R, et al., E3 ubiquitin ligase FBXW7 balances airway cell fates. Dev Biol. 2022 Mar;483:89-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427630
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: anti-p63 antibody [4A4] (CM163)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 2I: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 2I

Specimen 2J: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 2J Similar as in the control.

Specimen 4A: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 4A

Specimen 4B: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 4B Similar as in the control.

Specimen 4C: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Notch1tm1Agt/Notch1tm1Agt, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 4C Similar as in the control.

Specimen 5A: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 5A

Specimen 5B: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 5B Similar as in the control.

Specimen 5C: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Klf5tm1Jaw/Klf5tm1Jaw, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present 5C

Specimen S4A: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Shhtm1(EGFP/cre)Cjt/Shh+, Tgif1tm1Caw/Tgif1+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present Regionally restricted S4A Expressed in the basal layer.

Specimen S4B: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Shhtm1(EGFP/cre)Cjt/Shh+, Tgif1tm1Caw/Tgif1+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present Regionally restricted S4B Expressed in the basal layer, similar as in the control.

Specimen S4C: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7tm1Iaai, Shhtm1(EGFP/cre)Cjt/Shh+, Tgif1tm1Caw/Tgif1tm1Caw (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present Regionally restricted S4C Expressed in the basal layer, similar as in the control.

Specimen S5A: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present S5A

Specimen S5B: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Notch1tm1Agt/Notch1tm1Agt, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present S5B Similar as in the control.

Specimen S6A: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Present S6A

Specimen S6B: embryonic day 18.5; Fbxw7tm1Iaai/Fbxw7+, Klf5tm1Jaw/Klf5tm1Jaw, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Krt5 (assay MGI:7427631).
Structure Cell Type Level Pattern Image Note
TS26: trachea epithelium basal cell of epithelium of trachea Ambiguous S6B Decreased expression compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory