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Gene Expression Data
Assay Details
Assay
Reference: J:266596 Kersbergen A, et al., Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427514
Gene symbol: Cldn4
Gene name: claudin 4
Antibody: anti-Claudin 4 (ZMD.306) (36-4800)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 2G Grhl2 delta/+: embryonic day 16.5; Grhl2tm2.1Jane/Grhl2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Cldn4; green - Ctnnb1 (assay MGI:7427523).
Structure Level Pattern Image Note
TS24: bronchiole epithelium Present 2G upper right , 2G upper left
Specimen 2G Grhl2 delta/-: embryonic day 16.5; Grhl2tm1.1Jane/Grhl2tm2.1Jane, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Cldn4; green - Ctnnb1 (assay MGI:7427523).
Structure Level Pattern Image Note
TS24: bronchiole epithelium Absent 2G lower left , 2G lower right Complete absence of expression in distal epithelium.
Specimen S2E Grhl2 delta/+: embryonic day 16.5; Grhl2tm2.1Jane/Grhl2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Cldn4; green - Ctnnb1 (assay MGI:7427523).
Structure Level Pattern Image Note
TS24: lobar bronchus epithelium Present S2E upper right , S2E upper left
Specimen S2E Grhl2 delta/-: embryonic day 16.5; Grhl2tm1.1Jane/Grhl2tm2.1Jane, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Cldn4; green - Ctnnb1 (assay MGI:7427523).
Structure Level Pattern Image Note
TS24: lobar bronchus epithelium Present S2E lower right , S2E lower left Similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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