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Gene Expression Data
Assay Details
Assay
Reference: J:45426 DiLeone RJ, et al., An extensive 3' regulatory region controls expression of Bmp5 in specific anatomical structures of the mouse embryo. Genetics. 1998 Jan;148(1):401-8
Assay type: RNA in situ
MGI Accession ID: MGI:7425006
Gene symbol: Bmp5
Gene name: bone morphogenetic protein 5
Probe: Bmp5 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C: embryonic day 14.5-15.5 (more )
Structure Level Pattern Image Note
TS23: manubrium sterni Present Regionally restricted 2C Expressed in the rostral manubrium.
TS23: sternebra Present 2C
Specimen 2F: embryonic day 14.5-15.5 (more )
Structure Level Pattern Image Note
TS23: genital tubercle Present Regionally restricted 2F Expressed in the tip.
Specimen 2I: embryonic day 14.5-15.5 (more )
Structure Level Pattern Image Note
TS23: thyroid cartilage Present 2I
Specimen 2L: embryonic day 14.5-15.5 (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Present 2L
Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pinna mesenchyme condensation Present 3A
TS22: temporal bone petrous part Present 3A
Specimen 3B: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: temporal bone petrous part Present 3B Similar as in the wild-type.
TS22: pinna mesenchyme condensation Trace 3B Dramatically reduced expression compared with the wild-type.
Specimen 3C: embryonic day 14.5; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS22: temporal bone petrous part Present 3C Similar as in the wild-type.
TS22: pinna mesenchyme condensation Trace 3C Dramatically reduced expression compared with the wild-type.
Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thyroid gland Present 3D
TS22: respiratory system cartilage Present Regionally restricted 3D Expressed in the thyroid cartilage.
Specimen 3E: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: respiratory system cartilage Trace Regionally restricted 3E Dramatically reduced expression in the thyroid cartilage.
TS22: thyroid gland Present 3E Similar as in the wild-type.
Specimen 3F: embryonic day 14.5; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS22: thyroid gland Present 3F Similar as in the wild-type.
TS22: respiratory system cartilage Weak Regionally restricted 3F Dramatically reduced expression in the thyroid cartilage.
Specimen 3G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: perichondrium Present 3G Expressed in the perichondrium of the sternum and ribs.
Specimen 3H: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: perichondrium Present Regionally restricted 3H Reduced expression in the sternum perichondrium, whereas levels remained normal around the ribs.
Specimen 3I: embryonic day 14.5; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS22: perichondrium Weak 3I Reduced expression in both the sternum perichondrium and rib perichondrium.
Specimen 3J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: genital tubercle Present 3J
Specimen 3K: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: genital tubercle Absent 3K
Specimen 3L: embryonic day 14.5; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS22: genital tubercle Present 3L Similar as in the wild-type.
Specimen 3M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung mesenchyme Present 3M
TS22: lung epithelium Ambiguous 3M Little expression was seen.
Specimen 3N: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: lung mesenchyme Weak 3N Greatly reduced expression compared with the wild-type.
TS22: lung epithelium Present 3N Ectopic expression was seen.
Specimen 3O: embryonic day 15.0; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Present 3O Similar as in the wild-type.
TS23: lung epithelium Ambiguous 3O Similar as in the wild-type.
Specimen 3P: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: intestine mesenchyme Present Regionally restricted 3P Expressed in the mesenchyme surrounding the epithelium.
Specimen 3Q: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: intestine mesenchyme Present Regionally restricted 3Q Expressed in the mesenchyme surrounding the epithelium, similar as in the wild-type.
Specimen 3R: embryonic day 15.0; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS23: intestine mesenchyme Present Regionally restricted 3R Expressed in the mesenchyme surrounding the epithelium, similar as in the wild-type.
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal cartilage Present
TS22: limb digit Present Regionally restricted Expressed around the tips.
Specimen not shown: embryonic day 14.5; Bmp5se-30DThWb/Bmp5se-30DThWb (more )
Structure Level Pattern Image Note
TS22: limb digit Present Regionally restricted Expressed around the tips, similar as in the wild-type.
TS22: nasal cartilage Present Similar as in the wild-type.
Specimen not shown: embryonic day 14.5; Bmp5se-4CHLd/Bmp5se-4CHLd (more )
Structure Level Pattern Image Note
TS22: limb digit Present Regionally restricted Expressed around the tips, similar as in the wild-type.
TS22: nasal cartilage Present Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory