About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7424897
Gene symbol: Prss56
Gene name: serine protease 56
Probe: Prss56 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1 - Prss56: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted 1j , 1k Expression is restricted to the inner ONL-OECs; the outer ONL-OECs do not shown expression.
TS24: olfactory nerve olfactory ensheathing cell Absent 1j , 1l The mucosal OECs lack expression.
TS24: trigeminal nerve Schwann cell Absent 1j , 1m The Schwann cells lack expression.
Specimen S10 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Absent S10G , S10H The mucosal OECs lack expression.
Specimen S10 - E13 - I1: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: main olfactory bulb layer olfactory ensheathing cell Present S10I1 , S10J1 Expression is restricted to the olfactory nerve layer OECs within two cell diameters of the olfactory bulb.
Specimen S10 - E13 - I2: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve olfactory ensheathing cell Absent S10I2 , S10J2 The mucosal OECs lack expression.
Specimen S13A: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted S13A , S13A1 Expression is restricted to the inner ONL-OECs; the outer ONL-OECs do not shown expression.
Specimen S13B: embryonic day 16.5; Ptprz1tm1Mno/Ptprz1tm1Mno (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted S13B , S13B1 Expression is restricted to the inner ONL-OECs; this expression is stronger in the mutant compared to wild type.
Specimen S14I: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted S14I1 , S14I Expression is restricted to the inner ONL-OECs; the outer ONL-OECs do not shown expression.
Specimen S14J: embryonic day 16.5; Ptntm1Tmu/Ptntm1Tmu (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted S14J , S14J1 Expression is restricted to the inner ONL-OECs; the outer ONL-OECs do not shown expression. Expression levels in the mutant are comparable to those seen in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory