Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Actbtm1(icre)Ksak
Name:	actin, beta; targeted mutation 1, Kenji Sakimura
MGI ID:	MGI:7423624
Synonyms:	Actb-iCre
Gene:	Actb  Location: Chr5:142888870-142892509 bp, - strand  Genetic Position: Chr5, 81.8 cM
Alliance:	Actbtm1(icre)Ksak page

Germline Transmission:	Earliest citation of germline transmission: J:267307
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Actbtm1(icre)Ksak expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Actb (MGI:87904)     The targeting construct inserted the improved cre recombinase gene. (J:267307)

Activity:	Tissue activity of this recombinase allele
Driver:	Actb (mouse) Summary of all recombinase alleles driven by Actb. Alliance mouse Actb gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actb Mutation:	51 strains or lines available

Original:	J:267307 Zhou L, et al., Deletion of exons encoding carboxypeptidase domain of Nna1 results in Purkinje cell degeneration (pcd) phenotype. J Neurochem. 2018 Nov;147(4):557-572
All:	4 reference(s)