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Gene Expression Data
Assay Details
Assay
Reference: J:235128 Katayama Y, et al., CHD8 haploinsufficiency results in autistic-like phenotypes in mice. Nature. 2016 Sep 29;537(7622):675-679
Assay type: RT-PCR
MGI Accession ID: MGI:7413085
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Probe: Chd8-pI, Chd8-pJ
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Rplp0.
Results Image: ED2a
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
E10.5 WB +/+ E10.5 TS17: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E10.5 WB +/deltaSL E10.5 TS17: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E10.5 WB +/+ E10.5 TS17: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E10.5 WB +/deltaL E10.5 TS17: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
E14.5 WB +/+ E14.5 TS22: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E14.5 WB +/deltaSL E14.5 TS22: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E14.5 WB +/+ E14.5 TS22: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E14.5 WB +/deltaL E14.5 TS22: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
E18.5 WB +/+ E18.5 TS26: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E18.5 WB +/deltaSL E18.5 TS26: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
E18.5 WB +/+ E18.5 TS26: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
E18.5 WB +/deltaL E18.5 TS26: brain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
OB +/+ P w 9 TS28: main olfactory bulb Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
OB +/deltaSL P w 9 TS28: main olfactory bulb Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
OB +/+ P w 9 TS28: main olfactory bulb Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
OB +/deltaL P w 9 TS28: main olfactory bulb Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
CTX +/+ P w 9 TS28: cerebral cortex Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
CTX +/deltaSL P w 9 TS28: cerebral cortex Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
CTX +/+ P w 9 TS28: cerebral cortex Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
CTX +/deltaL P w 9 TS28: cerebral cortex Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
HIP +/+ P w 9 TS28: hippocampus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
HIP +/deltaSL P w 9 TS28: hippocampus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
HIP +/+ P w 9 TS28: hippocampus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
HIP +/deltaL P w 9 TS28: hippocampus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
STR +/+ P w 9 TS28: corpus striatum Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
STR +/deltaSL P w 9 TS28: corpus striatum Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
STR +/+ P w 9 TS28: corpus striatum Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
STR +/deltaL P w 9 TS28: corpus striatum Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
TH +/+ P w 9 TS28: thalamus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
TH +/deltaSL P w 9 TS28: thalamus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
TH +/+ P w 9 TS28: thalamus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
TH +/deltaL P w 9 TS28: thalamus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
HY +/+ P w 9 TS28: hypothalamus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
HY +/delta SL P w 9 TS28: hypothalamus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
HY +/+ P w 9 TS28: hypothalamus Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
HY +/deltaL P w 9 TS28: hypothalamus Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/+ P w 9 TS28: midbrain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/deltaSL P w 9 TS28: midbrain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
MB +/+ P w 9 TS28: midbrain Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
MB +/deltaL P w 9 TS28: midbrain Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
CB +/+ P w 9 TS28: cerebellum Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
CB +/deltaSL P w 9 TS28: cerebellum Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
CB +/+ P w 9 TS28: cerebellum Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
CB +/deltaL P w 9 TS28: cerebellum Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
P +/+ P w 9 TS28: pons Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
P +/deltaSL P w 9 TS28: pons Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
P +/+ P w 9 TS28: pons Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
P +/deltaL P w 9 TS28: pons Weak (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
Notes:
(a) The level of expression was ~50% that of wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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