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Gene Expression Data
Assay Details
Assay
Reference: J:290961 Chen F, et al., YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells. EMBO J. 2019 May 15;38(10)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7408314
Gene symbol: Tnnt1
Gene name: troponin T1, skeletal, slow
Results
Specimen 1J Ctrl: embryonic day 18.5; Yy1tm2.1Yshi/Yy1+ (more )
Note: Double labeled: red - Tnnt1; green - Laminin staining.
Structure Level Pattern Image Note
TS26: diaphragm Present 1J Ctrl
Specimen 1J cKO: embryonic day 18.5; Pax7tm1(cre)Mrc/Pax7+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: red - Tnnt1; green - Laminin staining.
Structure Level Pattern Image Note
TS26: diaphragm Present 1J cKO Massive loss of muscle fibers was seen.
Specimen 1M Ctrl: embryonic day 19.5; Yy1tm2.1Yshi/Yy1+ (more )
Note: Double labeled: red - Tnnt1; green - Laminin staining.
Structure Level Pattern Image Note
TS26: hindlimb muscle Present 1M Ctrl
Specimen 1M cKO: embryonic day 19.5; Pax7tm1(cre)Mrc/Pax7+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: red - Tnnt1; green - Laminin staining.
Structure Level Pattern Image Note
TS26: hindlimb muscle Present 1M cKO Each muscle appeared slightly smaller and the number of positive fibers was also decreased (54%) compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory