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Gene Expression Data
Assay Details
Assay
Reference: J:290961 Chen F, et al., YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells. EMBO J. 2019 May 15;38(10)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7408313
Gene symbol: Yy1
Gene name: YY1 transcription factor
Antibody: anti-YY1
Results
Specimen 1B Ctrl: embryonic day 12.5; Yy1tm2.1Yshi/Yy1+ (more )
Note: Double labeled: green - Yy1; red - Pax7 (assay MGI:7408312).
Structure Level Pattern Image Note
TS20: myotome Present 1B Ctrl YY1 , 1B Ctrl merge Coexpressed with Pax7 in progenitor cells.
Specimen 1B cKO: embryonic day 12.5; Pax7tm1(cre)Mrc/Pax7+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: green - Yy1; red - Pax7 (assay MGI:7408312).
Structure Level Pattern Image Note
TS20: myotome Present Regionally restricted 1B cKO YY1 , 1B cKO merge No expression in Pax7-expressing progenitors.
Specimen 1C Ctrl: embryonic day 12.5; Yy1tm2.1Yshi/Yy1+ (more )
Note: Double labeled: green - Yy1; red - Pax7 (assay MGI:7408312).
Structure Level Pattern Image Note
TS20: limb musculature Present 1C Ctrl merge , 1C Ctrl YY1 Coexpressed with Pax7 in progenitor cells.
TS20: limb Present Ubiquitous 1C Ctrl merge , 1C Ctrl YY1
Specimen 1C cKO: embryonic day 12.5; Pax7tm1(cre)Mrc/Pax7+, Yy1tm2.1Yshi/Yy1tm2.1Yshi (more )
Note: Conditional mutant. Double labeled: green - Yy1; red - Pax7 (assay MGI:7408312).
Structure Level Pattern Image Note
TS20: limb Present Regionally restricted 1C cKO merge , 1C cKO YY1 No expression in Pax7-expressing progenitors.
TS20: limb musculature Present Regionally restricted 1C cKO merge , 1C cKO YY1 No expression in Pax7-expressing progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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