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Gene Expression Data
Assay Details
Assay
Reference: J:330265 Seth A, et al., Gene dosage changes in KCTD13 result in penile and testicular anomalies via diminished androgen receptor function. FASEB J. 2022 Nov;36(11):e22567
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388492
Gene symbol: Kctd13
Gene name: potassium channel tetramerisation domain containing 13
Antibody: anti-Kctd13 (HPA043524)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2F: embryonic day 18.5 (more )
Note: wild type
Structure Level Pattern Image Note
TS26: urethra of male Strong 2F
TS26: genital tubercle of male Strong Regionally restricted 2F Expression is seen in the epithelia lamina.
TS26: preputial gland of male Strong 2F

Specimen 2G: embryonic day 18.5 (more )
Note: wild type
Structure Level Pattern Image Note
TS26: urethra of male Strong 2G
TS26: genital tubercle of male Strong Regionally restricted 2G Expression is seen in the epithelia lamina.

Specimen 2H/I: postnatal adult (more )
Note: wild type
Structure Level Pattern Image Note
TS28: penile urethra Present 2I , 2H Expression is observed in penile urethra and epithelia lamina.

Specimen 2J: postnatal adult; Kctd13em1Djla/Kctd13em1Djla (more )
Structure Level Pattern Image Note
TS28: urethra of male Absent 2J

Specimen 2K: embryonic day 18.5 (more )
Note: wild type
Structure Level Pattern Image Note
TS26: seminiferous cord Present 2K

Specimen 2L: postnatal day 5 (more )
Note: wild type
Structure Level Pattern Image Note
TS28: seminiferous tubule Strong 2L
TS28: interstitium of the testis Present Single cells 2L Expression is seen in some interstitial cells.

Specimen 2M/N: postnatal adult (more )
Note: wild type
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present 2M , 2N
TS28: Sertoli cell Sertoli cell Present 2M , 2N
TS28: spermatocyte Present 2N , 2M
TS28: spermatid Trace 2M , 2N There is minimal expression in round spermatids, none in elongated spermatids.

Specimen 2O: postnatal adult; Kctd13em1Djla/Kctd13em1Djla (more )
Structure Level Pattern Image Note
TS28: testis Absent 2O

Specimen 4C +/+: postnatal (more )
Structure Level Pattern Image Note
TS28: interstitium of the testis Present 4C +/+
TS28: spermatocyte Present 4C +/+
TS28: spermatogonium Present 4C +/+
TS28: spermatid Present 4C +/+ Expression seen in round spermatids.
TS28: spermatozoon Absent 4C +/+ No staining seen in sperm.

Specimen 4C -/-: postnatal; Kctd13em1Djla/Kctd13em1Djla (more )
Structure Level Pattern Image Note
TS28: testis Absent 4C -/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory