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Gene Expression Data
Assay Details
Assay
Reference: J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7388143
Gene symbol: Npm1
Gene name: nucleophosmin 1
Results
Specimen 1C B23 GV: postnatal adult (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS28: primary oocyte Present Regionally restricted 1C GV (merged) , 1C GV B23 Expression in nucleoli.
Specimen 1C B23 MII: postnatal adult (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS28: secondary oocyte Present Regionally restricted 1C MII B23 , 1C MII (merged) Expression in nucleoli.
Specimen 1C B23 1-cell: embryonic day 0.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted 1C 1-cell (merged) , 1C 1-cell B23 Expression in nucleoli.
Specimen 1C B23 2-cell: embryonic day 1.0 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present Regionally restricted 1C 2-cell (merged) , 1C 2-cell B23 Expression in nucleoli.
Specimen 1C B23 4-cell: embryonic day 2.0 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present Regionally restricted 1C 4-cell (merged) , 1C 4-cell B23 Expression in nucleoli.
Specimen 1C B23 8-cell: embryonic day 2.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted 1C 8-cell (merged) , 1C 8-cell B23 Expression in nucleoli.
Specimen 1C B23 morula: embryonic day 3.0 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 1C morula (merged) , 1C morula B23 Expression in nucleoli.
Specimen 1C B23 blastocyst: embryonic day 3.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 1C blastocyst B23 , 1C blastocyst (merged) Expression in nucleoli.
Specimen 2B E2.5 WT B23: embryonic day 2.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Regionally restricted 2B E2.5 WT Merged , 2B E2.5 WT B23
Specimen 2B E2.5 Dcaf13-/- B23: embryonic day 2.5; Dcaf13em1Hyfn/Dcaf13em1Hyfn (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Weak Regionally restricted 2B E2.5 Dcaf13-/- B23 , 2B E2.5 Dcaf13-/- Merged Nucleolar expression weakened compared wild type.
Specimen 2B E3.5 WT B23: embryonic day 3.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 2B E3.5 WT Merged , 2B E3.5 WT B23
Specimen 2B E3.5 Dcaf13-/- B23: embryonic day 3.5; Dcaf13em1Hyfn/Dcaf13em1Hyfn (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS4: embryo Weak Regionally restricted 2B E3.5 Dcaf13-/- B23 , 2B E3.5 Dcaf13-/- Merged Nucleolar expression weakened compared wild type.
Specimen 2B E4.5 WT B23: embryonic day 4.5 (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS6: embryo Present Regionally restricted 2B E4.5 WT Merged , 2B E4.5 WT B23
Specimen 2B E4.5 Dcaf13-/- B23: embryonic day 4.5; Dcaf13em1Hyfn/Dcaf13em1Hyfn (more )
Note: Double labeled: red - B23 (Npm1); green - Dcaf13 (assay MGI:7388141).
Structure Level Pattern Image Note
TS6: embryo Weak Regionally restricted 2B E4.5 Dcaf13-/- B23 , 2B E4.5 Dcaf13-/- Merged Nucleolar expression weakened compared wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory