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Gene Expression Data
Assay Details
Assay
Reference: J:226736 Li X, et al., Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384804
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5D +/+: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present Regionally restricted 5D Foxo3a+/+;Fancd2+/+ Merge , 5D Foxo3a+/+;Fancd2+/+ Expression is in neural stem cells.

Specimen 5D DKO: postnatal week 8; Fancd2tm1Hou/Fancd2tm1Hou, Foxo3tm1.1Rdp/Foxo3tm1.1Rdp (more )
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Present Regionally restricted 5D Foxo3a-/-;Fancd2-/- Merge , 5D Foxo3a-/-;Fancd2-/- The number of neural stem cells in this mutant was significantly decreased compared with that of wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory