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Gene Expression Data
Assay Details
Assay
Reference: J:311142 Sun H, et al., Gpr125 Marks Distinct Cochlear Cell Types and Is Dispensable for Cochlear Development and Hearing. Front Cell Dev Biol. 2021;9:690955
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384739
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 1A: embryonic day 15.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1A Specification of Myo7a+ hair cells had occurred in the basal turn.
Specimen 1B/B' Apex: embryonic day 15.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1B , 1B' Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 1C/C' Middle: embryonic day 15.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1C' , 1C Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 1D/D' Base: embryonic day 15.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1D' , 1D Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 1E/E' Apex: embryonic day 15.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1E' , 1E Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 1F/F' Middle: embryonic day 15.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1F' , 1F Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 1G/G' Base: embryonic day 15.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 1G , 1G' Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 2A: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2A
TS26: cochlear duct epithelium cochlear outer hair cell Present 2A
Specimen 2B Apex: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2B
TS26: cochlear duct epithelium cochlear outer hair cell Present 2B
Specimen 2C Apex: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2C
TS26: cochlear duct epithelium cochlear outer hair cell Present 2C
Specimen 2D Apex: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2D
TS26: cochlear duct epithelium cochlear outer hair cell Present 2D
Specimen 2E Apex: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2E
TS26: cochlear duct epithelium cochlear outer hair cell Present 2E
Specimen 2F Middle: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2F
TS26: cochlear duct epithelium cochlear outer hair cell Present 2F
Specimen 2G Middle: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2G
TS26: cochlear duct epithelium cochlear outer hair cell Present 2G
Specimen 2H Middle: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2H
TS26: cochlear duct epithelium cochlear outer hair cell Present 2H
Specimen 2I Middle: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2I
TS26: cochlear duct epithelium cochlear outer hair cell Present 2I
Specimen 2J Base: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2J
TS26: cochlear duct epithelium cochlear outer hair cell Present 2J
Specimen 2K Base: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2K
TS26: cochlear duct epithelium cochlear outer hair cell Present 2K
Specimen 2L Base: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2L
TS26: cochlear duct epithelium cochlear outer hair cell Present 2L
Specimen 2M Base: embryonic day 18.5; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 2M
TS26: cochlear duct epithelium cochlear outer hair cell Present 2M
Specimen 3A/A': postnatal day 0; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3A' , 3A
TS27: cochlear duct epithelium cochlear outer hair cell Present 3A' , 3A
Specimen 3B/B'/B": postnatal day 4; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 3B" , 3B , 3B'
TS28: cochlear duct epithelium cochlear outer hair cell Present 3B" , 3B , 3B'
Specimen 3C/C': postnatal day 0; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 3C' , 3C
TS27: cochlear duct epithelium cochlear outer hair cell Present 3C' , 3C
Specimen 3D/D': postnatal day 4; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 3D , 3D'
TS28: cochlear duct epithelium cochlear outer hair cell Present 3D , 3D'
Specimen 3E/E': postnatal day 30; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 3E' , 3E
TS28: cochlear duct epithelium cochlear outer hair cell Present 3E' , 3E
Specimen 3F/F': postnatal day 30; Adgra3tm1Dgen/Adgra3+ (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 3F , 3F'
TS28: cochlear duct epithelium cochlear outer hair cell Present 3F , 3F'
Specimen 4B: postnatal day 0 (more )
Note: Double labeled: blue - Myo7a; red - Adgra3 (assay MGI:7384743).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4B
TS27: organ of Corti cochlear outer hair cell Present 4B
Specimen 4C: postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; green - Adgra3 (assay MGI:7384688); red - Adgra3 (assay MGI:7384743).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4C
TS27: organ of Corti cochlear outer hair cell Present 4C
Specimen 4D/D'/D": postnatal day 0 (more )
Note: Double labeled: blue - Myo7a; red - Adgra3 (assay MGI:7384743).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4D , 4D' , 4D"
TS27: organ of Corti cochlear outer hair cell Present 4D , 4D' , 4D"
Specimen 4E/E'/E": postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; green - Adgra3 (assay MGI:7384688); red - Adgra3 (assay MGI:7384743).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4E' , 4E , 4E"
TS27: organ of Corti cochlear outer hair cell Present 4E' , 4E , 4E"
Specimen 4F/F'/F": postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Double labeled: blue - Myo7a; green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4F" , 4F , 4F'
TS27: organ of Corti cochlear outer hair cell Present 4F" , 4F , 4F'
Specimen 4G/G'/G": postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; green - Adgra3 (assay MGI:7384688); red - Polr2a (assay MGI:7384744).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 4G , 4G' , 4G"
TS27: organ of Corti cochlear outer hair cell Present 4G , 4G' , 4G"
Specimen 6Q: embryonic day 15.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 6Q Specification of Myo7a+ hair cells had occurred only in the basal turn.
Specimen 6R: embryonic day 15.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS23: cochlear duct epithelium cochlea auditory hair cell Present Regionally restricted 6R Specification of Myo7a+ hair cells had occurred only in the basal turn, similar as in the wild-type.
Specimen 6S: embryonic day 18.5 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 6S
TS26: cochlear duct epithelium cochlear outer hair cell Present 6S
Specimen 6T: embryonic day 18.5; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS26: cochlear duct epithelium cochlear inner hair cell Present 6T Similar as in the wild-type.
TS26: cochlear duct epithelium cochlear outer hair cell Present 6T Similar as in the wild-type.
Specimen 6U: postnatal day 0 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 6U
TS27: cochlear duct epithelium cochlear outer hair cell Present 6U
Specimen 6V: postnatal day 0; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS27: cochlear duct epithelium cochlear inner hair cell Present 6V Similar as in the wild-type.
TS27: cochlear duct epithelium cochlear outer hair cell Present 6V Similar as in the wild-type.
Specimen 6W: postnatal day 4 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6W
TS28: cochlear duct epithelium cochlear outer hair cell Present 6W
Specimen 6X: postnatal day 4; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6X Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present 6X Similar as in the wild-type.
Specimen 6Y: postnatal day 30 (more )
Note: Double labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6Y
TS28: cochlear duct epithelium cochlear outer hair cell Present 6Y
Specimen 6Z: postnatal day 30; Adgra3tm1Dgen/Adgra3tm1Dgen (more )
Note: Triple labeled: blue - Myo7a; red - Cd44 (assay MGI:7384738); green - Adgra3 (assay MGI:7384688).
Structure Cell Type Level Pattern Image Note
TS28: cochlear duct epithelium cochlear inner hair cell Present 6Z Similar as in the wild-type.
TS28: cochlear duct epithelium cochlear outer hair cell Present 6Z Similar as in the wild-type.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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