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Gene Expression Data
Assay Details
Assay
Reference: J:316543 Kim JS, et al., Reciprocal localization of transcription factors YY1 and CP2c in spermatogonial stem cells and their putative roles during spermatogenesis. Acta Histochem. 2016 Sep;118(7):685-692
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7384675
Gene symbol: Yy1
Gene name: YY1 transcription factor
Antibody: Anti-YY1 (EPR4652; ab109237)
Detection system: Secondary antibody coupled to alkaline phosphatase
Results
Specimen 1C: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: germ cell of testis Present Regionally restricted 1C , 1C' Staining identified 37.5% of gonocytes were immunopositive.
TS22: Sertoli cell Sertoli cell Present Regionally restricted 1C' , 1C Staining identified 86% of Sertoli cells were immunopositive.
TS22: testis mesenchyme mesenchymal cell Strong Regionally restricted 1C , 1C' Mesenchymal cells surrounding the testicular cords were strongly stained in the nuclei.
Specimen 2A: postnatal week 12 (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 2A
TS28: testis male germ line stem cell Present 2A Yy1 was localized strictly to the nucleus.
TS28: spermatocyte Present 2A
TS28: spermatid Present Regionally restricted 2A Some cells were immunolabeled.
TS28: spermatogonium Present Regionally restricted 2A Some cells were immunolabeled.
TS28: spermatozoon Absent 2A
Specimen 2C: postnatal week 12 (more )
Note: Double labeled: blue - YY1; brown - Tfcp2 (assay MGI:7384677).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 2C
TS28: testis male germ line stem cell Present 2C Yy1 was localized strictly to the nucleus.
TS28: spermatocyte Present 2C
TS28: spermatid Present Regionally restricted 2C Some cells were immunolabeled.
TS28: spermatogonium Present Regionally restricted 2C Some cells were immunolabeled.
TS28: spermatozoon Absent 2C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
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