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Gene Expression Data
Assay Details
Assay
Reference: J:33415 Gruda MC, et al., Expression of FosB during mouse development: normal development of FosB knockout mice. Oncogene. 1996 May 16;12(10):2177-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7380300
Gene symbol: Fosb
Gene name: FBJ osteosarcoma oncogene B
Antibody: anti-Fos B
Results
Specimen 1b: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: scapula Very strong Regionally restricted 1b Expression is in the hypertrophied chondrogenic layer and is absent in resting or proliferating cartilage. Expression is throughout the medullary cavity and in the zone of calcifying cartilage.
TS25: long bone Present Regionally restricted 1b Expression is in bony and cartilaginous areas of the epiphyseal growth plate.

Specimen 1e: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: mandible Present Regionally restricted 1e Expression is throughout the medullary cavity and in the zone of calcifying cartilage.

Specimen 1h: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: metatarsal bone Very strong Regionally restricted 1h Expression is in the hypertrophied chondrogenic layer.
TS25: foot Present Regionally restricted 1h Expression is in the subcutaneous tissue in the fore-and hind-foot.
TS25: hand Present Regionally restricted 1h Expression is in the subcutaneous tissue in the fore-and hind-foot.

Specimen 2Aa: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis basal layer Present 2Aa
TS25: epidermis granular layer Present 2Aa
TS25: vibrissa inner root sheath Present 2Aa
TS25: vibrissa outer root sheath Present 2Aa

Specimen 2Ac: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: intestine epithelium Present 2Ac

Specimen 2Ba: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lobar bronchus epithelium Present 2Ba
TS25: blood vessel endothelium Present Regionally restricted 2Ba Expression is in endothelial cells lining the arteries of the lung.
TS25: lung vascular element Present Regionally restricted 2Ba Expression is in endothelial cells lining the arteries of the lung.

Specimen 2Bc: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: liver Strong Regionally restricted 2Bc , 2Ba Expression is in the stroma.

Specimen 3C +/+: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: gland Present 3C +/+ Expression is in serous glands.

Specimen 3C -/-: postnatal newborn; Fosbtm1Brv/Fosbtm1Brv (more )
Structure Level Pattern Image Note
TS27: gland Absent 3C -/-

Specimen not shown E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vertebral cartilage condensation Present

Specimen not shown E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: long bone Very strong Regionally restricted Expression is in the hypertrophied chondrogenic layer.
TS25: rib Very strong Regionally restricted Expression is in the hypertrophied chondrogenic layer.
TS25: vertebra Very strong Regionally restricted Expression is in the hypertrophied chondrogenic layer.
TS25: head skin Present
TS25: limb skin Present
TS25: trunk skin Absent

Specimen not shown P0: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: liver Strong
TS27: bone Weak
TS27: intestine Weak
TS27: lung Weak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory