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Gene Expression Data
Assay Details
Assay
Reference: J:323190 Guo T, et al., KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 Feb 25;11:e74595
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7367118
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen 3I,J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 3J , 3I
Specimen 3K,L: embryonic day 13.5; Kdm6btm1.1Rbo/Kdm6btm1.1Rbo, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Strong 3K , 3L Increased expression in palatal mesenchyme compared to controls.
Specimen 3N,O: embryonic day 13.5 (more )
Note: Double labeled: red - H2ax; green - Edu.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 3O , 3N
Specimen 3P,Q: embryonic day 13.5; Kdm6btm1.1Rbo/Kdm6btm1.1Rbo, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - H2ax; green - Edu.
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Strong Regionally restricted 3Q , 3P Expression significantly increased in Edu-positive cells in palatal mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory