Gene Expression Data
Assay Details
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Assay
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Reference:
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J:161878
Hudon V, et al., Renal tumour suppressor function of the Birt-Hogg-Dube syndrome gene product folliculin. J Med Genet. 2010 Mar;47(3):182-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7334886
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Gene symbol:
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Rps6
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Gene name:
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ribosomal protein S6
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Results
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Specimen
5D:
postnatal adult; FlcnGt(RRX115)Byg/Flcn +
(more  )
Note: multilocular and large cyst area
Specimen
5D:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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multilocular and large cyst area
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: metanephros |
epithelial cell |
Strong |
Regionally restricted |
5D
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Expressed in the epithelial cells lining multilocular and large cysts from mutant polycystic kidneys. Expression was very low in the surrounding normal tissue.
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Specimen
5E:
postnatal adult; FlcnGt(RRX115)Byg/Flcn +
(more )
Note: small single cyst area
Specimen
5E:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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small single cyst area
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: metanephros |
epithelial cell |
Present |
Regionally restricted |
5E
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No expression in epithelial cells lining the small single cyst. High expression in the epithelial cells lining multilocular and large cysts from mutant polycystic kidneys. Expression was very low in the surrounding normal tissue.
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Specimen
5F:
postnatal adult; FlcnGt(RRX115)Byg/Flcn +
(more )
Note: small single cyst area
Specimen
5F:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Note:
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small single cyst area
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: metanephros |
epithelial cell |
Present |
Regionally restricted |
5F
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No expression in epithelial cells lining the small single cyst. High expression in the epithelial cells lining multilocular and large cysts from mutant polycystic kidneys. Expression was very low in the surrounding normal tissue.
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Specimen
S5A:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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FlcnGt(RRX115)Byg/Flcn+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: metanephros |
Weak |
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S5A
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Expression was very low in the normal tissue.
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Analysis Tools
