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Gene Expression Data
Assay Details
Assay
Reference: J:203995 Lee S, et al., Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7333018
Gene symbol: Trp63
Gene name: transformation related protein 63
Results
Specimen 4G control: embryonic day 18.5 (more )
Note: Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4G left
Specimen 4G shd-/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis keratinocyte Present Widespread 4G middle Expressed throughout the epidermis.
TS26: epidermis basal layer keratinocyte Present 4G middle
Specimen 4G shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4G right Normal epidermis thickness was restored in lateral (barrier-restored) regions.
Specimen 4L shd+/+; Er+/-: embryonic day 18.5; SfnEr/Sfn+ (more )
Note: Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4L left
Specimen 4L shd+/-; Er+/- dorsal: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Dorsal back skin. Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis keratinocyte Present Widespread 4L middle Expression was greatly expanded in dorsal regions.
Specimen 4L shd+/-; Er+/- lateral: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Lateral back skin. Double labeled: green - Trp63; red - Itgb4 (assay MGI:7333017).
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present 4L right Expression in lateral regions was similar as in the wild-type control.
Specimen not shown wild type: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: epidermis basal layer keratinocyte Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory