About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:203995 Lee S, et al., Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7333006
Gene symbol: Itgb4
Gene name: integrin beta 4
Results
Specimen 2A control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2A left Marked the border between the epidermis and dermis.

Specimen 2A -/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2A right Marked the border between the epidermis and dermis.

Specimen 2C control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2C left Marked the border between the epidermis and dermis.

Specimen 2C -/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2C right Marked the border between the epidermis and dermis.

Specimen 2D control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2D left Marked the border between the epidermis and dermis.

Specimen 2D -/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2D right Marked the border between the epidermis and dermis.

Specimen 2F control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - pH3.
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2F left Marked the border between the epidermis and dermis.

Specimen 2F -/-: embryonic day 18.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Itgb4; red - pH3.
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2F right Marked the border between the epidermis and dermis. Proliferation was no longer restricted to the basal layer and that suprabasal keratinocytes continued to divide.

Specimen 3F control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3F left Marked the border between the epidermis and dermis.

Specimen 3F shd+/-; Er+/-: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3F right Marked the border between the epidermis and dermis.

Specimen 3G control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3G left Marked the border between the epidermis and dermis.

Specimen 3G shd+/-; Er+/-: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3G right Marked the border between the epidermis and dermis.

Specimen 3H control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3H left Marked the border between the epidermis and dermis.

Specimen 3H shd+/-; Er+/-: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3H right Marked the border between the epidermis and dermis.

Specimen 3I control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3I left Marked the border between the epidermis and dermis.

Specimen 3I shd+/-; Er+/-: embryonic day 18.5; Kdf1shd/Kdf1+, SfnEr/Sfn+ (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 3I right Marked the border between the epidermis and dermis.

Specimen 4B control: embryonic day 14.5 (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS22: epidermis basal layer Present 4B left Marked the border between the epidermis and dermis.

Specimen 4B -/-: embryonic day 14.5; Kdf1shd/Kdf1shd (more )
Note: Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS22: epidermis basal layer Present 4B right Marked the border between the epidermis and dermis.

Specimen 4H control: embryonic day 18.5 (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4H left Marked the border between the epidermis and dermis.

Specimen 4H shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Krt14 (assay MGI:7333005).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4H right Marked the border between the epidermis and dermis.

Specimen 4I control: embryonic day 18.5 (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4I left Marked the border between the epidermis and dermis.

Specimen 4I shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4I right Marked the border between the epidermis and dermis.

Specimen 4J control: embryonic day 18.5 (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4J left Marked the border between the epidermis and dermis.

Specimen 4J shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4J right Marked the border between the epidermis and dermis.

Specimen 4K control: embryonic day 18.5 (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4K left Marked the border between the epidermis and dermis.

Specimen 4K shd-/-; p63+/-: embryonic day 18.5; Kdf1shd/Kdf1shd, Trp63tm2Brd/Trp63+ (more )
Note: Lateral back skin. Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 4K right Marked the border between the epidermis and dermis.

Specimen 6B control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Krt5 (assay MGI:7333020).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6B left Marked the border between the epidermis and dermis.

Specimen 6B GT/shd: embryonic day 18.5; Kdf1shd/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Krt5 (assay MGI:7333020).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6B middle Marked the border between the epidermis and dermis.

Specimen 6B GT/GT: embryonic day 18.5; Kdf1tm1a(EUCOMM)Wtsi/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Krt5 (assay MGI:7333020).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6B right Marked the border between the epidermis and dermis.

Specimen 6C control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6C left Marked the border between the epidermis and dermis.

Specimen 6C GT/shd: embryonic day 18.5; Kdf1shd/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6C middle Marked the border between the epidermis and dermis.

Specimen 6C GT/GT: embryonic day 18.5; Kdf1tm1a(EUCOMM)Wtsi/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Krt10 (assay MGI:7333007).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6C right Marked the border between the epidermis and dermis.

Specimen 6D control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6D left Marked the border between the epidermis and dermis.

Specimen 6D GT/shd: embryonic day 18.5; Kdf1shd/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6D middle Marked the border between the epidermis and dermis.

Specimen 6D GT/GT: embryonic day 18.5; Kdf1tm1a(EUCOMM)Wtsi/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Loricrin (assay MGI:7333009).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6D right Marked the border between the epidermis and dermis.

Specimen 6E control: embryonic day 18.5 (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6E left Marked the border between the epidermis and dermis.

Specimen 6E GT/shd: embryonic day 18.5; Kdf1shd/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6E middle Marked the border between the epidermis and dermis.

Specimen 6E GT/GT: embryonic day 18.5; Kdf1tm1a(EUCOMM)Wtsi/Kdf1tm1a(EUCOMM)Wtsi (more )
Note: Double labeled: green - Itgb4; red - Flg (assay MGI:7333008).
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 6E right Marked the border between the epidermis and dermis.

Specimen 7G: embryonic day 16.5 (more )
Note: Double labeled: green - Itgb4; red - Kdf1 (assay MGI:7333023).
Structure Level Pattern Image Note
TS24: epidermis basal layer Present 7G Marked the border between the epidermis and dermis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory