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Gene Expression Data
Assay Details
Assay
Reference: J:199602 Fotaki V, et al., Foxg1 is required to limit the formation of ciliary margin tissue and Wnt/beta-catenin signalling in the developing nasal retina of the mouse. Dev Biol. 2013 Aug 15;380(2):299-313
Assay type: RNA in situ
MGI Accession ID: MGI:7332936
Gene symbol: Sfrp2
Gene name: secreted frizzled-related protein 2
Probe: Sfrp2 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 2A Expressed in most retinal cells.

Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 2B Expressed in most retinal cells.

Specimen 2C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 2C Expressed in most retinal cells.

Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 2D Expressed in most retinal cells.

Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present 2E Expressed in most retinal cells.

Specimen 2A': embryonic day 11.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS19: retina Present 2A' Expressed in most retinal cells.

Specimen 2B': embryonic day 11.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS19: retina Present 2B' Expressed in most retinal cells.

Specimen 2C': embryonic day 11.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS19: retina Present 2C' Expressed in most retinal cells. Only temporal retinal pigment epithelium was present.

Specimen 2D': embryonic day 11.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS19: retina Present 2D' Expressed in most retinal cells. Only temporal retinal pigment epithelium was present.

Specimen 2E': embryonic day 11.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS19: retina Present 2E' Expressed in most retinal cells. Only temporal retinal pigment epithelium was present.

Specimen 2F: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: neural retina retinal ganglion cell Present Regionally restricted 2F Expressed in all retinal cells in the proliferating layer and most of the retinal ganglion cells of the differentiating layer of the central retina.

Specimen 2G: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: neural retina retinal ganglion cell Present Regionally restricted 2G Expressed in all retinal cells in the proliferating layer and most of the retinal ganglion cells of the differentiating layer of the central retina.
TS20: lens primordium Present 2G

Specimen 2H: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: neural retina retinal ganglion cell Present Regionally restricted 2H Expressed in all retinal cells in the proliferating layer and most of the retinal ganglion cells of the differentiating layer of the central retina. No staining in the ciliary margin tissue.
TS20: lens primordium Present 2H

Specimen 2I: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: neural retina retinal ganglion cell Present Regionally restricted 2I Expressed in all retinal cells in the proliferating layer and most of the retinal ganglion cells of the differentiating layer of the central retina.

Specimen 2F': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: neural retina Present 2F'

Specimen 2G': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: neural retina Present 2G' The mutant optic cup was not spherical. Abnormal retinal folds were clearly detected nasally.

Specimen 2H': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 2H'
TS20: neural retina Present 2H' The mutant optic cup was not spherical. Abnormal retinal folds were clearly detected nasally, with additional negative areas in mutants.

Specimen 2I': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 2I'
TS20: neural retina Present Regionally restricted 2I' The mutant optic cup was not spherical. Abnormal retinal folds were clearly detected nasally, with additional negative areas in mutants.

Specimen 2J': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 2J'
TS20: neural retina Present Regionally restricted 2J' Additional negative areas in mutants were seen.

Specimen 2K': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 2K'
TS20: neural retina Present Regionally restricted 2K' Additional negative areas in mutants were seen.

Specimen 2L': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: neural retina Present 2L'

Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens primordium Present 3B , 3B right
TS20: neural retina Present Regionally restricted 3B , 3B right No staining in the ciliary margin tissue.

Specimen 3B': embryonic day 12.5; Foxg1tm1M/Foxg1tm1M (more )
Structure Level Pattern Image Note
TS20: neural retina Present Regionally restricted 3B' right , 3B' Additional negative areas in mutants were seen.
TS20: lens primordium Present 3B'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory