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Gene Expression Data
Assay Details
Assay
Reference: J:216287 Czajkowski MT, et al., Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle. Dev Biol. 2014 Nov 15;395(2):307-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7331678
Gene symbol: Myh2
Gene name: myosin, heavy polypeptide 2, skeletal muscle, adult
Antibody: clone MY-32 (M4276)
Detection system: Secondary antibody
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 4A: embryonic day 13.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Lbx1tm3.1(cre)Cbm/Lbx1+, Mettm1Cbm/Met+ (more )
Note: Conditional mutant. Double labeled: green - Myh1 and Myh2; green - Cre reporter.
Structure Level Pattern Image Note
TS21: tongue extrinsic pre-muscle mass Present 4A Co-stained with somitic lineage beta-gal.
TS21: tongue intrinsic muscle Present 4A Co-stained with somitic lineage beta-gal.
Specimen 4B: embryonic day 13.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Mesp1tm2(cre)Ysa/Mesp1+, Mettm1Cbm/Met+ (more )
Note: Conditional mutant. Double labeled: green - Myh1 and Myh2; green - Cre reporter.
Structure Level Pattern Image Note
TS21: tongue extrinsic pre-muscle mass Present 4B Co-stained with cranial mesoderm lineage beta-gal.
TS21: tongue intrinsic muscle Present 4B Co-stained with cranial mesoderm lineage beta-gal.
Specimen 4C: embryonic day 13.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Lbx1tm3.1(cre)Cbm/Lbx1+, Mettm1Cbm/Mettm1Cbm (more )
Note: Conditional mutant. Double labeled: green - Myh1 and Myh2; green - Cre reporter.
Structure Level Pattern Image Note
TS21: tongue extrinsic pre-muscle mass Present 4C A complete absence of somitic lineage beta-gal+ cells was seen, with little change in size of the muscle.
TS21: tongue intrinsic muscle Present 4C A complete absence of somitic lineage beta-gal+ cells was seen, with little change in size of the muscle.
Specimen 4D: embryonic day 13.0; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Mesp1tm2(cre)Ysa/Mesp1+, Mettm1Cbm/Mettm1Cbm (more )
Note: Conditional mutant. Double labeled: green - Myh1 and Myh2; green - Cre reporter.
Structure Level Pattern Image Note
TS21: tongue extrinsic pre-muscle mass Weak 4D Expressed in residual muscles, with cranial mesoderm lineage beta-gal+ cells present.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory