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Gene Expression Data
Assay Details
Assay
Reference: J:149884 Kim T, et al., NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin-induced cell death. EMBO J. 2009 Jun 3;28(11):1612-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7331653
Gene symbol: Sort1
Gene name: sortilin 1
Results
Specimen 1Aa: postnatal day 1 (more )
Note: Double labeled: red - Sort1; green - Nradd (assay MGI:7331571).
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1Aa Merged , 1Aa Sortilin Co-immunolabeling was detected with Nradd in most dorsal root ganglion neurons.
Specimen 1Ac: postnatal day 1 (more )
Note: Double labeled: green - Sort1; red - Ngfr (assay MGI:7331654).
Structure Cell Type Level Pattern Image Note
TS27: dorsal root ganglion sensory neuron of dorsal root ganglion Present Regionally restricted 1Ac Merged , 1Ac Sortilin Expression was detected in most dorsal root ganglion neurons. A subpopulation of neurons was co-immunolabeled with Ngfr.
Specimen S1a: postnatal day 1 (more )
Note: Double labeled: green - Sort1; red - Nradd (assay MGI:7331571).
Structure Cell Type Level Pattern Image Note
TS27: spinal cord spinal cord motor neuron Present Regionally restricted S1a Sortilin , S1a merged Co-expression with Nradd was observed in a subset of spinal motor neurons.
Specimen S2B: embryonic day 15.5 (more )
Note: Double labeled: green - Sort1; red - Nradd (assay MGI:7331571).
Structure Cell Type Level Pattern Image Note
TS23: retina layer retinal ganglion cell Strong Regionally restricted S2B Merged , S2B Sortilin Expression was high in the ganglion cell layer. A subset of cells in the ganglion cell layer were co-labeled with Nradd.
Specimen S2C: postnatal day 1 (more )
Note: Double labeled: green - Sort1; red - Nradd (assay MGI:7331571).
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Weak Regionally restricted S2C Merged , S2C Sortilin Expression was markedly reduced in the ganglion cell layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory