About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:185804 Larkins CE, et al., Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia. Dev Biol. 2012 Jul 1;367(1):15-24
Assay type: RNA in situ
MGI Accession ID: MGI:7331400
Gene symbol: Dand5
Gene name: DAN domain family member 5, BMP antagonist
Probe: IMAGE clone 790229
Probe preparation: Antisense RNA
Results
Specimen 5D: embryonic day 7.5 (more )
Note: presomite stage
Structure Level Pattern Image Note
TS11: node Present 5D Right-sided asymmetry was seen (10 out of 19 embryos).

Specimen 5E: embryonic day 7.5; Arl13bhnn/Arl13bhnn (more )
Note: presomite stage
Structure Level Pattern Image Note
TS11: node Present 5E Slightly higher levels of expression in the left side (4 out 8 embryos).

Specimen not shown: embryonic day 7.5 (more )
Note: presomite stage
Structure Level Pattern Image Note
TS11: node Present No asymmetry was seen in 5 out of 19 embryos; left-sided in 4 (summarized in 5D).

Specimen not shown: embryonic day 7.5; Arl13bhnn/Arl13bhnn (more )
Note: presomite stage
Structure Level Pattern Image Note
TS11: node Present Right-sided asymmetry was seen in 2 out of 8 embryos; no asymmetry in 2 (summarized in 5E).

Specimen not shown: embryonic day 8.0 (more )
Note: 2-3 somites stage
Structure Level Pattern Image Note
TS12: node Present Right-sided asymmetry was seen in 25 out of 26 embryos; left-sided in 1 (summarized in 5D).

Specimen not shown: embryonic day 8.0; Arl13bhnn/Arl13bhnn (more )
Note: 2-3 somites stage
Structure Level Pattern Image Note
TS12: node Present Symmetric expression was seen in 2 out of 4 embryos, left-sided in 1, and right-sided in 1 (summarized in 5E).

Specimen not shown: embryonic day 8.0 (more )
Note: 4-5 somites stage
Structure Level Pattern Image Note
TS12: node Present Right-sided asymmetry was seen in 15 out of 16 embryos, symmetric expression in 1 (summarized in 5D).

Specimen not shown: embryonic day 8.0; Arl13bhnn/Arl13bhnn (more )
Note: 4-5 somites stage
Structure Level Pattern Image Note
TS12: node Present Symmetric expression was seen in 5 out of 6 embryos, right-sided in 1 (summarized in 5E).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/28/2024
MGI 6.13
The Jackson Laboratory