Elavl3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:308612 Deal KK, et al., Altered sacral neural crest development in Pax3 spina bifida mutants underlies deficits of bladder innervation and function. Dev Biol. 2021 Aug;476:173-188
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7331367
Gene symbol:	Elavl3
Gene name:	ELAV like RNA binding protein 3

Antibody:

Anti-HuC/D

Results

Specimen 6A Pax3+/+: embryonic day 14.5; Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Calca (assay MGI:7331380); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Present	Widespread	6A Pax3+/+ HuC/D , 6A Pax3+/+ Merge

Specimen 6A Pax3^Sp-d/Sp-d: embryonic day 14.5; Pax3^Sp-d/Pax3^Sp-d, Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Calca (assay MGI:7331380); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Weak		6A Pax3^Sp-d/Sp-d Merge , 6A Pax3^Sp-d/Sp-d HuC/D

Specimen 6A Pax3^Sp-d/+: embryonic day 14.5; Pax3^Sp-d/Pax3⁺, Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Calca (assay MGI:7331380); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Present	Widespread	6A Pax3^Sp-d/+ Merge , 6A Pax3^Sp-d/+ HuC/D

Specimen 6A Pax3^+/delta5: embryonic day 14.5; Pax3^tm1.1Sjc/Pax3⁺, Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Calca (assay MGI:7331380); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Present	Widespread	6A Pax3^+/delta5 HuC/D , 6A Pax3^+/delta5 Merge

Specimen 6A Pax3^Sp-d/delta5: embryonic day 14.5; Pax3^Sp-d/Pax3^tm1.1Sjc, Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Calca (assay MGI:7331380); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Present	Widespread	6A Pax3^Sp-d/delta5 Merge , 6A Pax3^Sp-d/delta5 HuC/D	No significant reductions in the amount of total immunolabeling was noted in the Pax3<Sp-d/delta5> pelvic ganglion neurons, despite the pronounced effect seen in Pax3<Sp-d/Sp-d> fetal mice.

Specimen 7 Pax3+/+: embryonic day 14.5; Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Th (assay MGI:7331393); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Present	Widespread	7Pax3^+/+ Merge , 7Pax3^+/+ HuC/D

Specimen 7 Pax3^Sp-d/Sp-d: embryonic day 14.5; Pax3^Sp-d/Pax3^Sp-d, Tg(Sox10-cre)1Sout/0, Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant. Triple labeled: blue - Elavl3 and Elavl4; green - Th (assay MGI:7331393); red - Cre reporter.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: pelvic ganglion	neuron	Weak		7Pax3^Sp-d/Sp-d HuC/D , 7Pax3^Sp-d/Sp-d Merge

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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