Gene Expression Image Detail

Reference

Figure

ID

J:308612 Deal KK, et al., Dev Biol. 2021 Aug;476:173-188

6

MGI:7327177

Image

Caption

(A) Confocal images of immunostained 14.5 dpc cryosections from Pax3 variant genotypes. (B) Plot of total pelvic ganglia area of neural crest derivatives labeled by tdTomato activated via Sox10-cre for each genotype class. (C) Plot of percent CGRP labeling within total HuC/D area for each genotype class. Each dot represents average values for an independent embryo measured from six pelvic ganglia sections.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.ydbio.2021.03.024 Dev Biol 476: 173-188, Deal KK; Chandrashekar AS; Beaman MM; Branch MC; Buehler DP; Conway SJ; Southard-Smith EM, Altered sacral neural crest development in Pax3 spina bifida mutants underlies deficits of bladder innervation and function. Copyright 2021.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A Pax3+/+ HuC/D	MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3+/+ CGRP	MGI:7331380 (Calca)
A Pax3+/+ Merge	MGI:7331380 (Calca) MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/Sp-d HuC/D	MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/Sp-d CGRP	MGI:7331380 (Calca)
A Pax3^Sp-d/Sp-d Merge	MGI:7331380 (Calca) MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/+ HuC/D	MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/+ CGRP	MGI:7331380 (Calca)
A Pax3^Sp-d/+ Merge	MGI:7331380 (Calca) MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^+/delta5 HuC/D	MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^+/delta5 CGRP	MGI:7331380 (Calca)
A Pax3^+/delta5 Merge	MGI:7331380 (Calca) MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/delta5 HuC/D	MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)
A Pax3^Sp-d/delta5 CGRP	MGI:7331380 (Calca)
A Pax3^Sp-d/delta5 Merge	MGI:7331380 (Calca) MGI:7331367 (Elavl3) MGI:7331372 (Elavl4)