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Gene Expression Data
Assay Details
Assay
Reference: J:173795 Hilliard S, et al., Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Dev Biol. 2011 May 15;353(2):354-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7330269
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (11562-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 5A/B/C: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep (more )
Note: Double labeled: red - Six2; green - Cdh1 (assay MGI:7330270).
Structure Level Pattern Image Note
TS22: cap mesenchyme Present 5A , 5B , 5C
Specimen 5D/E/F: embryonic day 14.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant. Double labeled: red - Six2; green - Cdh1 (assay MGI:7330270).
Structure Level Pattern Image Note
TS22: cap mesenchyme Present 5E , 5F , 5D Positive population appeared less condensed and at times forming a thicker cap around the poorly developed ureteric bud tip regions.
Specimen S3A/B/C: embryonic day 15.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep (more )
Note: Double labeled: red - Six2; green - Cdh1 (assay MGI:7330270).
Structure Level Pattern Image Note
TS23: cap mesenchyme Present S3C , S3B , S3A
Specimen S3D/E/F: embryonic day 15.5; Mdm2tm1.2Mep/Mdm2tm1.2Mep, Tg(Hoxb7-cre)5526Cmb/0 (more )
Note: Conditional mutant. Double labeled: red - Six2; green - Cdh1 (assay MGI:7330270).
Structure Level Pattern Image Note
TS23: cap mesenchyme Present S3E , S3D , S3F Positive population formed a thin layer around the dysmorphic ureteric bud regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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