Gene Expression Data
Assay Details
Assay
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Reference:
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J:320745
Ferguson CJ, et al., APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 Jan 6;82(1):90-105.e13
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7328851
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Gene symbol:
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Mki67
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Gene name:
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antigen identified by monoclonal antibody Ki 67
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Results
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Specimen
5M ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
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Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
postnatal day 11
|
Sex:
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Not Specified
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Type:
|
section
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Fixation:
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4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
5M Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
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Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
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Age:
|
postnatal day 11
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7A ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7A Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: cerebral cortex |
Present |
Regionally restricted |
7A Anapc7-/-
|
Expression outside of progenitor zones.
|
Specimen
7B ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
7B Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
optical section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: cortical plate |
Present |
Regionally restricted |
7B Anapc7-/- merge
,
7B Anapc7-/- Ki-67
|
Expression outside of progenitor zones.
|
Specimen
S7A ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
postnatal day 11
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS28: cerebellum external granule cell layer |
neural progenitor cell |
Present |
Regionally restricted |
S7A ctrl Ki-67
|
Expression restricted to proliferating granule cell precursors in outer EGL.
|
Specimen
S7A Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
postnatal day 11
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S7B ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 18.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: neocortex |
Present |
|
S7B ctril (right)
|
|
Specimen
S7B Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 18.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: neocortex |
Present |
Regionally restricted |
S7B Anapc7-/- (right)
|
Expression outside of progenitor zones.
|
Specimen
S7C ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S7C Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: telencephalon |
Present |
Regionally restricted |
S7C Anapc7-/-
|
Expression outside of progenitor zones.
|
Specimen
S7D ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: diencephalon |
Present |
|
S7D ctrl (upper)
,
S7D ctrl (lower)
|
|
Specimen
S7D Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: diencephalon |
Present |
Regionally restricted |
S7D Anapc7-/- (lower)
,
S7D Anapc7-/- (upper)
|
Expression outside of progenitor zones.
|
Specimen
S7E ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: brainstem |
Present |
|
S7E ctrl (lower)
,
S7E ctrl (upper)
|
|
Specimen
S7E Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: brainstem |
Present |
Regionally restricted |
S7E Anapc7-/- (upper)
,
S7E Anapc7-/- (lower)
|
Expression outside of progenitor zones.
|
Specimen
S7F ctrl:
(close )
Genetic Background:
|
involves: 129 * C57BL/6 * CBA
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7+
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S7F Anapc7-/-:
(close )
Genetic Background:
|
B6.129S6(CBA)-Anapc7tm1.1Azbi
|
Mutant Allele(s):
|
Anapc7tm1.1Azbi/Anapc7tm1.1Azbi
|
Age:
|
embryonic day 16.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS24: hindbrain |
Present |
Regionally restricted |
S7F Anapc7-/-
|
Expression outside of progenitor zones.
|
|