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Gene Expression Data
Assay Details
Assay
Reference: J:170203 Lague MN, et al., Decidual PTEN expression is required for trophoblast invasion in the mouse. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E936-46
Assay type: Western blot
MGI Accession ID: MGI:7328687
Gene symbol: Pten
Gene name: phosphatase and tensin homolog
Antibody: Anti-Pten (138G6; #9559)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 3_PTEN
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex Note
FL/FL non-pregnant 1 P adult TS28: uterus Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuFemale
FL/FL non-pregnant 2 P adult TS28: uterus Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuFemale
Fl/FL healthy d11.5 1 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuNot Specified uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Fl/FL healthy d11.5 2 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuNot Specified uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Fl/FL dying d11.5 1 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuNot Specified uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Fl/FL dying d11.5 2 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present involves: 129S4/SvJae * C57BL/6 Ptentm1Hwu/Ptentm1HwuNot Specified uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
CKO non-pregnant 1 P adult TS28: uterus Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuFemale Conditional mutant.
CKO non-pregnant 2 P adult TS28: uterus Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuFemale Conditional mutant.
CKO healthy d11.5 1 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuNot Specified Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
CKO healthy d11.5 2 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuNot Specified Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
CKO dying d11.5 1 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuNot Specified Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
CKO dying d11.5 2 E11.5 TS19: extraembryonic component
TS28: decidua
TS28: uterus 		Present (b) involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1HwuNot Specified Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Notes:
(a) An average 4.03-fold lower level of expression in nonpregnant and E11.5 pregnant uterine wall samples in conditional mutants.
(b) Reduced expression compared with the controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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