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Gene Expression Data
Assay Details
Assay
Reference: J:170203 Lague MN, et al., Decidual PTEN expression is required for trophoblast invasion in the mouse. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E936-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328670
Gene symbol: Pten
Gene name: phosphatase and tensin homolog
Antibody: Anti-Pten (138G6; #9559)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: postnatal adult; Ptentm1Hwu/Ptentm1Hwu (more )
Structure Cell Type Level Pattern Image Note
TS28: myometrium myometrial cell Present 2A
TS28: endometrium glandular epithelium glandular endometrial unciliated epithelial cell Present 2A
TS28: uterus stroma Present 2A

Specimen 2B: postnatal adult; Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1Hwu (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: endometrium glandular epithelium glandular endometrial unciliated epithelial cell Present Single cells 2B inset , 2B Loss of expression in some uterine glandular epithelial cells.
TS28: myometrium myometrial cell Trace 2B Nearly complete abrogation of expression.
TS28: uterus stroma Trace 2B Nearly complete abrogation of expression.

Specimen 2C uterus: postnatal adult; Ptentm1Hwu/Ptentm1Hwu (more )
Note: uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Structure Level Pattern Image Note
TS28: decidua Present 2C
TS28: myometrium Present 2C
TS28: uterus stroma Present 2C

Specimen 2C embryo: embryonic day 11.5; Ptentm1Hwu/Pten+ (more )
Structure Level Pattern Image Note
TS19: trophoblast giant cell Present 2C
TS19: labyrinthine zone Present 2C

Specimen 2D: postnatal adult; Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1Hwu (more )
Note: Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Structure Level Pattern Image Note
TS28: decidua Trace 2D Nearly complete abrogation of expression.
TS28: myometrium Trace 2D Nearly complete abrogation of expression.
TS28: uterus stroma Trace 2D Nearly complete abrogation of expression.

Specimen not shown: postnatal adult; Ptentm1Hwu/Ptentm1Hwu (more )
Structure Level Pattern Image Note
TS28: decidua Present
TS28: myometrium Present
TS28: uterus stroma Present

Specimen not shown: postnatal adult; Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1Hwu (more )
Note: Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Structure Level Pattern Image Note
TS28: decidua Trace Nearly complete abrogation of expression.
TS28: myometrium Trace Nearly complete abrogation of expression.
TS28: uterus stroma Trace Nearly complete abrogation of expression.

Specimen not shown: postnatal adult; Ptentm1Hwu/Ptentm1Hwu (more )
Structure Level Pattern Image Note
TS28: decidua Present
TS28: myometrium Present
TS28: uterus stroma Present

Specimen not shown: postnatal adult; Amhr2tm3(cre)Bhr/Amhr2+, Ptentm1Hwu/Ptentm1Hwu (more )
Note: Conditional mutant. uteri (including placenta and extraembryonic tissue) from E11.5 pregnant mice
Structure Level Pattern Image Note
TS28: decidua Trace Nearly complete abrogation of expression.
TS28: myometrium Trace Nearly complete abrogation of expression.
TS28: uterus stroma Trace Nearly complete abrogation of expression.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory