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Gene Expression Data
Assay Details
Assay
Reference: J:324706 Lu J, et al., Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328643
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Antibody: anti-p57Kip2 [EP2515Y] (ab75974)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 8C,C': postnatal day 0.5; Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Structure Level Pattern Image Note
TS27: lens Present Regionally restricted 8C' , 8C Expression distributed similarly to p27Kip1.
Specimen 8D,D': postnatal day 0.5; Tg(Cryaa-cre)10Mlr/0, Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: lens Present Regionally restricted 8D' , 8D Expression markely elevated in central region of lens compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory