About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:324706 Lu J, et al., Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328637
Gene symbol: Znhit1
Gene name: zinc finger, HIT domain containing 1
Antibody: anti-Znhit1 (HAP019043)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1C,C': embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Strong 1C , 1C'
TS21: lens fiber lens fiber cell Strong 1C , 1C'
Specimen 1D,D': postnatal day 0.5 (more )
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Strong 1D' , 1D
TS27: lens fiber lens fiber cell Strong 1D , 1D'
Specimen 1E,E': postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Weak 1E , 1E'
TS28: lens fiber lens fiber cell Weak 1E , 1E'
Specimen 1F,F': postnatal week 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Trace 1F' , 1F
TS28: lens fiber lens fiber cell Trace 1F , 1F'
Specimen 1G,G': postnatal week 12 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Trace 1G' , 1G
TS28: lens fiber lens fiber cell Trace 1G , 1G'
Specimen 2A,A': embryonic day 13.5; Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Strong 2A' , 2A
TS21: lens fiber lens fiber cell Strong 2A' , 2A
Specimen 2B,B': embryonic day 13.5; Tg(Cryaa-cre)10Mlr/0, Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Present 2B' , 2B Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
TS21: lens fiber lens fiber cell Present 2B , 2B' Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
Specimen 2C,C': postnatal day 0.5; Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Weak 2C' , 2C
TS27: lens fiber lens fiber cell Weak 2C , 2C'
Specimen 2D,D': postnatal day 0.5; Tg(Cryaa-cre)10Mlr/0, Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Trace 2D' , 2D Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
TS27: lens fiber lens fiber cell Trace 2D' , 2D Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory