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Gene Expression Data
Assay Details
Assay
Reference: J:248783 Xie WR, et al., An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment. J Neurosci. 2017 Sep 6;37(36):8583-8594
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7328541
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 3B1 lacZ/+: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Level Pattern Image Note
TS24: brainstem Present Regionally restricted 3B1 lacZ/+ Expression in microcellular tegmental, dorsolateral lemniscal and pontine nuclei.
TS24: rostral migratory stream Present 3B1 lacZ/+
Specimen 3B1 S193A/lacZ: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Structure Level Pattern Image Note
TS24: brainstem Present Regionally restricted 3B1 193A/lacZ Expression in microcellular tegmental, dorsolateral lemniscal and pontine nuclei.
TS24: rostral migratory stream Present 3B1 193A/lacZ
Specimen 3B2 lacZ/+: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Level Pattern Image Note
TS24: brainstem Present Regionally restricted 3B2 lacZ/+ Expression in parabrachial and paratrigeminal nuclei.
Specimen 3B2 S193A/lacZ: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Structure Level Pattern Image Note
TS24: brainstem Present Regionally restricted 3B2 193A/lacZ Expression in parabrachial and paratrigeminal nuclei.
Specimen 3B3 lacZ/+: embryonic day 16.5; Atoh1tm2Hzo/Atoh1+ (more )
Structure Level Pattern Image Note
TS24: cerebellum external granule cell layer Present 3B3 lacZ/+
TS24: brainstem Present Regionally restricted 3B3 lacZ/+ Expression in deep cerebellar and ventral cochlear nuclei.
Specimen 3B3 S193A/lacZ: embryonic day 16.5; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Structure Level Pattern Image Note
TS24: cerebellum external granule cell layer Present 3B3 193A/lacZ
TS24: brainstem Present Regionally restricted 3B3 193A/lacZ Expression in deep cerebellar and ventral cochlear nuclei.
Specimen 3C lacZ/+: postnatal day 0; Atoh1tm2Hzo/Atoh1+ (more )
Structure Level Pattern Image Note
TS27: pontine nucleus Present 3C lacZ/+ (left) , 3C lacZ/+ (right)
Specimen 3C lS193A/lacZ: postnatal day 0; Atoh1tm2Hzo/Atoh1tm7.1Hzo (more )
Structure Level Pattern Image Note
TS27: pontine nucleus Present 3C S193A/lacZ (left) , 3C S193A/lacZ (right)
TS27: rostral migratory stream Present 3C S193A/lacZ (right) , 3C S193A/lacZ (left) Partial defect in pontine neural migration shown by continued presence of anterior migratory stream.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory