Eya1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:320689 Xu J, et al., Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation. Front Cell Dev Biol. 2022;10:815249
Assay type:	RNA in situ
MGI Accession ID:	MGI:7328526
Gene symbol:	Eya1
Gene name:	EYA transcriptional coactivator and phosphatase 1

Probe:	Eya1 probe14
Probe preparation:	Antisense RNA

Results

4B +/+ ©

Specimen 4B +/+: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: cap mesenchyme	Present		4B +/+

4B Six1/+ ©

Specimen 4B Six1/+: embryonic day 11.5; Eya1^tm4(Six1)Px/Eya1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: cap mesenchyme	Present		4B Six1/+

Specimen 4B Six1/+;Six2-/-: embryonic day 11.5; Eya1^tm4(Six1)Px/Eya1⁺, Six2^tm1Gco/Six2^tm1Gco (more

)

Structure	Level	Pattern	Image	Note
TS19: cap mesenchyme	Present		4B Six1/+; Six2-/-	Expression domain was comparable to that seen in Six2-/- littermates, both of which were smaller in size than in control littermates.

4B Six2-/- ©

Specimen 4B Six2-/-: embryonic day 11.5; Six2^tm1Gco/Six2^tm1Gco (more

)

Structure	Level	Pattern	Image	Note
TS19: cap mesenchyme	Present		4B Six2-/-	Expression domain was smaller in size than in control littermates.

5A +/+ ©

Specimen 5A +/+: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: cap mesenchyme	Strong		5A +/+

5A Six1/+ ©

Specimen 5A Six1/+: embryonic day 12.5; Eya1^tm4(Six1)Px/Eya1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS20: cap mesenchyme	Strong		5A Six1/+

Specimen 5A Six1/+;Six2-/-: embryonic day 12.5; Eya1^tm4(Six1)Px/Eya1⁺, Six2^tm1Gco/Six2^tm1Gco (more

)

Structure	Level	Pattern	Image	Note
TS20: cap mesenchyme	Weak		5A Six1/+; Six2-/-	Only residual transcripts were observed.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23