Eya1^tm4(Six1)Px
Targeted Allele Detail

Summary

• Symbol: Eya1^tm4(Six1)Px
• Name: EYA transcriptional coactivator and phosphatase 1; targeted mutation 4, Pin-Xian Xu
• MGI ID: MGI:7328385
• Synonyms: Eya1^Six1
• Gene: Eya1 Location: Chr1:14239178-14380459 bp, - strand Genetic Position: Chr1, 4.31 cM
• Alliance: Eya1^tm4(Six1)Px page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157941
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Eya1^tm4(Six1)Px expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Six1 (MGI:102780)

• Mutation details: The endogenous start codon as well as the exon 1 was replaced with a promoterless Six1 coding sequence and a PGK-neo gene. (J:157941)

Expression

In Mice Carrying this Mutation:

29 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eya1 Mutation: 54 strains or lines available

References

• Original: J:157941 Nie X, et al., SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation. Development. 2010 Mar;137(5):755-65
• All: 2 reference(s)