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Gene Expression Data
Assay Details
Assay
Reference: J:228128 Zheng Z, et al., Timing of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7194-203
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328374
Gene symbol: Ar
Gene name: androgen receptor
Antibody: AR antibody (N-20; sc-816)
Assay notes: A Tyramide Signal Amplification kit was used to detect proteins.
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: urethral plate epithelium of male Strong 1B , 1A Expression is cytoplasmic.
TS21: genital tubercle mesenchyme of male Strong Regionally restricted 1B , 1A Expression is in the center of the genital tubercle.
Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: urethral plate epithelium of female Strong 1D , 1C Expression is cytoplasmic.
TS21: genital tubercle mesenchyme of female Strong Regionally restricted 1C , 1D Expression is in the center of the genital tubercle.
Specimen 1E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: genital tubercle of male Present 1E , 1F Expression is nuclear.
Specimen 1G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: genital tubercle of female Trace 1G , 1H
Specimen 1I: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: glans penis Strong Regionally restricted 1I Expression is strongest in the corpus cavernosum urethrae and the male urogenital mating protuberance ridge.
TS27: corpus cavernosum of glans penis Strong 1I
TS27: mesenchyme of glans penis Present 1I
TS27: prepuce mesenchyme of male Present 1I
Specimen 1K: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: glans clitoris Present Single cells 1K Expression is mostly cytoplasmic.
Specimen S2A: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: glans clitoris Present Single cells S2B , S2A Expression is mostly cytoplasmic.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory