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Gene Expression Data
Assay Details
Assay
Reference: J:326361 Li S, et al., Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7327512
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 8A': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo7a; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 8A'
Specimen 8B': postnatal day 1; Atoh1tm1(cre)Gan/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo7a; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 8B'
TS27: organ of Corti cochlear outer hair cell Present 8B'
Specimen 8D': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo7a; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti Deiter's cell Absent 8D'
TS27: organ of Corti pillar cell Absent 8D'
Specimen 8E': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo7a; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti Deiter's cell Absent 8E'
TS27: organ of Corti Hensen cell Absent 8E'
TS27: organ of Corti pillar cell Absent 8E'
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory