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Gene Expression Data
Assay Details
Assay
Reference: J:79855 Anderson RM, et al., Chordin and noggin promote organizing centers of forebrain development in the mouse. Development. 2002 Nov;129(21):4975-87
Assay type: RNA in situ
MGI Accession ID: MGI:7316483
Gene symbol: Shh
Gene name: sonic hedgehog
Results
Specimen 3B: embryonic day 7.75 (more )
Note: Headfold stage.
Structure Level Pattern Image Note
TS11: prechordal plate Present 3B
TS11: mesendoderm Present Regionally restricted 3B Expression was detected in all midline mesendoderm, including the rostral prechordal plate.
Specimen 3K: embryonic day 8.0 (more )
Note: Three-somite stage.
Structure Level Pattern Image Note
TS12: prechordal plate Present Regionally restricted 3K Expression was detected in rostral prechordal plate.
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: axial mesoderm Present Regionally restricted 4A Expression was detected in mesendoderm and prechordal plate.
TS13: future prosencephalon Present Regionally restricted 4A Expression was detected in rostral ventral neural midline.
Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present 4B
TS15: future forebrain Present Regionally restricted 4B Expression was detected in rostral ventral neural midline.
Specimen 4E: embryonic day 8.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nog+ (more )
Note: ~ 8-10 somites.
Structure Level Pattern Image Note
TS13: axial mesoderm Present Regionally restricted 4E Expression was detected in more caudal regions, but was absent from the rostral prechordal plate in the mutant.
TS13: future brain Present Regionally restricted 4E Expression was detected in more caudal regions, but was not detected in the rostral ventral neural midline.
Specimen 4F: embryonic day 9.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nog+ (more )
Note: ~20-25 somites.
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 4F Expression was detected in more caudal regions, but was not detected in the rostral ventral neural midline.
TS15: 1st branchial arch Absent 4F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory