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Gene Expression Data
Assay Details
Assay
Reference: J:309620 Tan C, et al., Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network. PLoS Genet. 2021 Sep;17(9):e1009785
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7314613
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Antibody: anti-Nkx-2.5 (N-19): sc-8697
Detection system: Secondary antibody
Results
Specimen 1D E9.5 Ctrl: embryonic day 9.5; Med30tm1.1Sev/Med30tm1.1Sev (more )
Note: Double labeled with Edu (red).
Structure Cell Type Level Pattern Image Note
TS15: primitive ventricle cardiac muscle cell Present 1D Ctrl E9.5
Specimen 1D E9.5 cKO: embryonic day 9.5; Med30tm1.1Sev/Med30tm1.1Sev, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled with Edu (red).
Structure Cell Type Level Pattern Image Note
TS15: primitive ventricle cardiac muscle cell Present 1D cKO E9.5
Specimen 1D E10.5 Ctrl: embryonic day 10.5; Med30tm1.1Sev/Med30tm1.1Sev (more )
Note: Double labeled with Edu (red).
Structure Cell Type Level Pattern Image Note
TS17: primitive ventricle cardiac muscle cell Present 1D Ctrl E10.5
Specimen 1D E10.5 cKO: embryonic day 10.5; Med30tm1.1Sev/Med30tm1.1Sev, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled with Edu (red).
Structure Cell Type Level Pattern Image Note
TS17: primitive ventricle cardiac muscle cell Present 1D cKO E10.5 In this mutant cardiomyocyte proliferation was decreased in the compact zone and trabeculae of both ventricles relative to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory