Gene Expression Data
Assay Details
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Assay
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Reference:
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J:324238
Lo M, et al., CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022 May 3;13(1):2407
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7312085
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Gene symbol:
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Shh
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Gene name:
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sonic hedgehog
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Probe:
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Shh probe216
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Probe preparation:
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labelled with digoxigenin RNA
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Results
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Specimen
2a Shh E10.5 Control:
embryonic day 10.5
(more  )
Specimen
2a Shh E10.5 Control:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2a Shh E10.5 Cnpy4-/-:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cnpy4tm1Lex/Cnpy4tm1Lex
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2a Shh E11.5 Control:
embryonic day 11.5
(more )
Specimen
2a Shh E11.5 Control:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2a Shh E11.5 Cnpy4-/-:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cnpy4tm1Lex/Cnpy4tm1Lex
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2a Shh E12.5 Control:
embryonic day 12.5
(more )
Specimen
2a Shh E12.5 Control:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
2a Shh E12.5 Cnpy4-/-:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cnpy4tm1Lex/Cnpy4tm1Lex
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
S3 Shh E10.5:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cnpy4tm1Lex/Cnpy4tm1Lex
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: hindlimb bud |
Weak |
Regionally restricted |
S3_Shh E10.5
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Authors report reduced expresson in a minority of mutant hindlimb buds.
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Specimen
S3 Shh E11.5:
(close )
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Genetic Background:
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involves: 129 * C57BL/6J
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Mutant Allele(s):
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Cnpy4tm1Lex/Cnpy4tm1Lex
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: hindlimb bud |
Weak |
Regionally restricted |
S3_Shh E11.5
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Authors report reduced expresson in a minority of mutant hindlimb buds.
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Analysis Tools