Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:271028 Albers E, et al., Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality. Cell Rep. 2018 Sep 18;24(12):3274-3284
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7311707
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175; #9661)
Detection system:	horseradish peroxidase

Results

2C Pich WT ©

Specimen 2C Pich WT: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Trace		2C Pich WT

2C Pich Het ©

Specimen 2C Pich Het: embryonic day 10.5; Ercc6l^tm1.1Ajlc/Ercc6l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Trace		2C Pich Het

2C Pich KO ©

Specimen 2C Pich KO: embryonic day 10.5; Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		2C Pich KO	Increase in number of expressing cells.

S1G Pich Het ©

Specimen S1G Pich Het: embryonic day 10.5; Ercc6l^tm1.1Ajlc/Ercc6l⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Trace		S1G Pich Het

S1G Pich KO ©

Specimen S1G Pich KO: embryonic day 10.5; Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S1G Pich KO	Increase in number of expressing cells.

S2D Pich WT ©

Specimen S2D Pich WT: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: embryo	Ambiguous		S2D Pich WT	Expression in specimen not described.

S2D Pich KO ©

Specimen S2D Pich KO: embryonic day 11.5; Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc (more

)

Structure	Level	Pattern	Image	Note
TS19: embryo	Present		S2D Pich KO	Increase in number of expressing cells.

S3D Pich WT ©

Specimen S3D Pich WT: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Ambiguous		S3D Pich WT	Expression in specimen not described.

S3D Pich KO ©

Specimen S3D Pich KO: embryonic day 12.5; Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc (more

)

Structure	Level	Pattern	Image	Note
TS20: embryo	Present		S3D Pich KO	Increase in number of expressing cells.

S5B WT Caspase-3 (left) ©

Specimen S5B Casp3 WT (left): embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Trace		S5B WT Caspase-3 (left)

S5B WT Caspase-3 (right) ©

Specimen S5B Casp3 WT (right): embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Ambiguous		S5B WT Caspase-3 (right)	Expression in specimen not described.

Specimen S5B Casp3 Ptch KO: embryonic day 10.5; Ercc6l^tm1.1Ajlc/Ercc6l^tm1.1Ajlc (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S5B Pich KO Caspase-3

Specimen S5B Casp3 Trp53 Het (left): embryonic day 10.5; Ercc6l^tm1.2Ajlc/Ercc6l^tm1.2Ajlc, Trp53^tm1Tyj/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S5B Trp53 Het Caspase-3 (left)

Specimen S5B Casp3 Trp53 Het (right): embryonic day 10.5; Ercc6l^tm1.2Ajlc/Ercc6l^tm1.2Ajlc, Trp53^tm1Tyj/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S5B Trp53 Het Caspase-3 (right)

Specimen S5B Casp3 Trp53 KO (left): embryonic day 10.5; Ercc6l^tm1.2Ajlc/Ercc6l^tm1.2Ajlc, Trp53^tm1Tyj/Trp53^tm1Tyj (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S5B Trp53 KO Caspase-3 (left)

Specimen S5B Casp3 Trp53 KO (right): embryonic day 10.5; Ercc6l^tm1.2Ajlc/Ercc6l^tm1.2Ajlc, Trp53^tm1Tyj/Trp53^tm1Tyj (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		S5B Trp53 KO Caspase-3 (right)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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