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Gene Expression Data
Assay Details
Assay
Reference: J:82084 Van de Putte T, et al., Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome. Am J Hum Genet. 2003 Feb;72(2):465-70
Assay type: RNA in situ
MGI Accession ID: MGI:7310091
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Results
Specimen 2C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: facial neural crest Present Regionally restricted 2C Expression in trigeminal or facial neural crest migrating from brain plate toward maxillary component of first and second branchial arches.
TS13: trigeminal neural crest Present Regionally restricted 2C Expression in trigeminal or facial neural crest migrating from brain plate toward maxillary component of first and second branchial arches.

Specimen 2D: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Structure Level Pattern Image Note
TS13: future brain neural crest Present Regionally restricted 2D Expression in cranial neural crest cells that have not delaminated, remaining clustered at junctional zone between neural and surface ectoderm, without significant migration.

Specimen 2E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present Regionally restricted 2E At level of headfold, expression in neural crest cells that have initiated migration.

Specimen 2F: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Structure Level Pattern Image Note
TS13: neural crest Present Regionally restricted 2F Expression in cells that have not delaminated or initiated migration.

Specimen 2G: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: migrating neural crest Present Regionally restricted 2G At level of heart, expression in neural crest cells that have initiated migration.

Specimen 2H: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Structure Level Pattern Image Note
TS13: neural crest Present Regionally restricted 2H Expression in cells that have not delaminated or initiated migration.

Specimen 3A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac neural crest Present Regionally restricted 3A Expression in postotic vagal region.

Specimen 3B: embryonic day 8.5; Zeb2tm1.2Yhi/Zeb2tm1.2Yhi (more )
Structure Level Pattern Image Note
TS13: cardiac neural crest Absent 3B Expression lost from postotic vagal region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory