About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:313926 Cichon MA, et al., Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs. Front Cell Dev Biol. 2020;8:608876
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7294410
Gene symbol: H2-M2
Gene name: histocompatibility 2, M region locus 2
Antibody: anti-I-A/I-E [M5/114] (556999)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. I-A/I-E antibody MGI:7294398 may have been used in this assay.
Results
Specimen 1D skin section MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Cell Type Level Pattern Image Note
TS28: epidermis Langerhans cell Present 1D skin section MHCII
TS28: dermis dendritic cell Present 1D skin section MHCII
Specimen 1D epidermal sheets MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 1D epidermal sheets MHCII Co-expression with Rtn1a.
Specimen 2B pd1: postnatal day 1 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 2B pd1 Expression upregulated in most Rtna1a+ cells.
Specimen 2B pd3: postnatal day 3 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 2B pd3 Expression upregulated in most Rtna1a+ cells.
Specimen 2B pd7: postnatal day 7 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 2B pd7 Expression upregulated in most Rtna1a+ cells.
Specimen 3C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: thymus Present Regionally restricted 3C MHCII inset (upper) , 3C MHCII , 3C MHCII inset (lower) Expression co-localized with Rtn1a in majority of cells.
Specimen 4C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: lymph node Present Regionally restricted 4C MHCII , 4C MHCII inset Expression co-localized with Rtn1a in majority of cells.
Specimen 5C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: spleen Present Regionally restricted 5C MHCII inset (lower) , 5C MHCII , 5C MHCII inset (upper) Expression co-localized with Rtn1a in a minute population of cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory