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Gene Expression Data
Assay Details
Assay
Reference: J:313926 Cichon MA, et al., Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs. Front Cell Dev Biol. 2020;8:608876
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7294410
Gene symbol: H2-M2
Gene name: histocompatibility 2, M region locus 2
Antibody: anti-I-A/I-E [M5/114] (556999)
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. I-A/I-E antibody MGI:7294398 may have been used in this assay.
Results
Specimen 1D skin section MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Cell Type Level Pattern Image Note
TS28: epidermis Langerhans cell Present 1D skin section MHCII
TS28: dermis dendritic cell Present 1D skin section MHCII
Specimen 1D epidermal sheets MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 1D epidermal sheets MHCII Co-expression with Rtn1a.
Specimen 2B pd1: postnatal day 1 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 2B pd1 Expression upregulated in most Rtna1a+ cells.
Specimen 2B pd3: postnatal day 3 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 2B pd3 Expression upregulated in most Rtna1a+ cells.
Specimen 2B pd7: postnatal day 7 (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 2B pd7 Expression upregulated in most Rtna1a+ cells.
Specimen 3C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: thymus Present Regionally restricted 3C MHCII inset (upper) , 3C MHCII , 3C MHCII inset (lower) Expression co-localized with Rtn1a in majority of cells.
Specimen 4C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: lymph node Present Regionally restricted 4C MHCII , 4C MHCII inset Expression co-localized with Rtn1a in majority of cells.
Specimen 5C MHCII: postnatal adult (more )
Note: Double labeled: green - H2-M2 (MHCII); red - Rtn1 (assay MGI:7294409).
Structure Level Pattern Image Note
TS28: spleen Present Regionally restricted 5C MHCII inset (lower) , 5C MHCII , 5C MHCII inset (upper) Expression co-localized with Rtn1a in a minute population of cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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