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Gene Expression Data
Assay Details
Assay
Reference: J:308709 Duran Alonso MB, et al., Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea. Front Cell Dev Biol. 2021;9:679325
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7287921
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 5I: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present 5I Expressed in the sensory hair cells.
Specimen 5J: embryonic day 14.0; Meis2tm1.1Mtor/Meis2tm1.1Mtor, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present 5J Abnormal morphology of the cochlear duct in mutants, with increased sized patches of hair cells in the apex.
Specimen 5K/M: embryonic day 14.0 (more )
Structure Cell Type Level Pattern Image Note
TS22: cochlear duct epithelium cochlear inner hair cell Present 5M , 5K
TS22: cochlear duct epithelium cochlear outer hair cell Present 5M , 5K
Specimen 5L/N: embryonic day 14.0; Meis2tm1.1Mtor/Meis2tm1.1Mtor, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: cochlear duct epithelium cochlear inner hair cell Present 5N , 5L An enlarged cochlear duct with clusters of hair cells at the apex.
TS22: cochlear duct epithelium cochlear outer hair cell Present 5N , 5L An extra row of outer hair cells in the basal turn was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory