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Gene Expression Data
Assay Details
Assay
Reference: J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7287493
Gene symbol: Akt1
Gene name: thymoma viral proto-oncogene 1
Antibody: Anti-Akt (pan) (11E7) #4685
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4G Sox9flox/+: embryonic day 13.5; Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 4G Anti-Akt Sox9flox/+
Specimen 4G 11Enh-Cre; Sox9flox/flox: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Ambiguous 4G Anti-Akt 11Enh-Cre; Sox9flox/flox
Specimen 4H Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present 4H Anti-Akt Sox9flox/+
Specimen 4H 11Prom-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Ambiguous 4H Anti-Akt 11Prom-Cre; Sox9flox/flox
Specimen S6 Sox9flox/+; Ptenflox/+: embryonic day 14.5; Ptentm2Mak/Pten+, Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present S6_Anti-Akt Sox9flox/+;Ptenflox/+
Specimen S6 11Prom-Cre; Sox9flox/flox; Pten+/+: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Ambiguous S6_Anti-Akt 11Prom-Cre;Sox9flox/flox;Pten+/+
Specimen S6 11Prom-Cre; Sox9flox/flox; Ptenflox/flox: embryonic day 14.5; Ptentm2Mak/Ptentm2Mak, Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Ambiguous S6_Anti-Akt 11Prom-Cre;Sox9flox/flox;Ptenflox/flox
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory