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Gene Expression Data
Assay Details
Assay
Reference: J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type: RNA in situ
MGI Accession ID: MGI:7286334
Gene symbol: Mmp13
Gene name: matrix metallopeptidase 13
Probe: Mmp13 probe12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Present 1D Mmp13 Sox9flox/+
Specimen 1D 11Enh-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Absent 1D Mmp13 11Enh-Cre; Sox9flox/flox
Specimen 3D Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Present 3D Mmp13 Sox9flox/+
Specimen 3D 11Prom-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Weak 3D Mmp13 11Prom-Cre; Sox9flox/flox
Specimen S2C Sox9flox/wt: embryonic day 15.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS23: humerus chondrocyte Present S2C Mmp13 Sox9flox/+
TS23: humerus Present Regionally restricted S2C Mmp13 Sox9flox/+ Expression was detected in the primary ossification center.
Specimen S2C 11Enh-Cre; Sox9flox/flox: embryonic day 15.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS23: humerus chondrocyte Absent S2C Mmp13 11Enh-Cre;Sox9flox/flox
TS23: humerus Present Regionally restricted S2C Mmp13 11Enh-Cre;Sox9flox/flox Expression was maintained in the conditional mutant primary ossification center.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory